tobramycin
Drug class
Active ingredient: tobramycin
- Other aminoglycosidesATC code: J01GB01Source: ATC
Allergy cross-reactivity
Deoxystreptamine aminoglycosides
Risk level: High
Basis: Shared 2-deoxystreptamine core structure
Other active ingredients in the same group:
- amikacin
- gentamicin
- neomycin
- netilmicin
Notes: Group members share a deoxystreptamine nucleus; within-group cross-reactivity is high (>=50%), especially for contact dermatitis. Streptomycin is excluded (streptidine nucleus, ~1-5%). Consult a specialist.
Source: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6789510/
Cross-reactivity risk is not definitive; consult an allergy/infectious disease specialist.
Breastfeeding
LactMed
Risk level: Compatible
Poorly excreted into milk and poorly absorbed orally; compatible.
Source: https://www.ncbi.nlm.nih.gov/books/NBK501115/
Breastfeeding safety requires individual assessment; consult a physician.