tetracaine
Drug class
Active ingredient: tetracaine
- Esters of aminobenzoic acidATC code: N01BASource: ATC
Allergy cross-reactivity
Ester local anesthetics
Risk level: High
Basis: Ester local anesthetics are metabolized to para-aminobenzoic acid (PABA), highly antigenic, producing within-group cross-reactivity.
Other active ingredients in the same group:
- benzocaine
- procaine
Notes: Within-group cross-reactivity is significant. True IgE-mediated LA allergy is rare (<1%); most reactions are caused by the preservative methylparaben. Do not give a binary safe/allergic answer; consult a specialist.
Source: https://www.ncbi.nlm.nih.gov/books/NBK430894/
Cross-reactivity risk is not definitive; consult an allergy/infectious disease specialist.