heparin
Drug class
Active ingredient: heparin
- Heparin groupATC code: B01ABSource: ATC
Allergy cross-reactivity
Heparins / LMWH (delayed-type skin hypersensitivity)
Risk level: High
Basis: Broad cross-reactivity between UFH and LMWH in delayed-type (type IV) cutaneous hypersensitivity, independent of molecular weight.
Other active ingredients in the same group:
- dalteparin
- enoxaparin
- nadroparin
- tinzaparin
Notes: HIT (heparin-induced thrombocytopenia) is a SEPARATE immune/antibody-mediated entity, distinct from this delayed-type cutaneous reaction. Never give a binary safe/allergic verdict; refer to a specialist.
Source: https://pubmed.ncbi.nlm.nih.gov/17573880/
Cross-reactivity risk is not definitive; consult an allergy/infectious disease specialist.
Breastfeeding
LactMed
Risk level: Compatible
Large molecule, does not pass into milk and not orally bioavailable; compatible.
Source: https://www.ncbi.nlm.nih.gov/books/NBK500921/
Breastfeeding safety requires individual assessment; consult a physician.